Can't manually edit SCSS code - outside changes

That’s all I wanted to know, because without having a page opened it doesn’t work. Then there must be an other reason! Just checked it with the latest version of Pinegrow on one of my iMacs and it works flawlessly here.
You can when you have a backup of your site try: Page > Customize & Update Bootstrap Theme
Say yes to all appearing panels.
and then try it again.